Browsing by Author "Sari, Ismail"
Now showing items 1-20 of 24
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Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in Daily Practice: A Multicenter Experience
Tekgunduz, Emre; Goker, Hakan; Kaynar, Leylagul; Sari, Ismail; Pala, Cigdem; Dogu, Mehmet Hilmi; Ozturk, Erman; Turgut, Burhan; Korkmaz, Serdal; Tetik, Aysegul; Buyukasik, Yahya; Hacioglu, Sibel Kabukcu; Bozdag, Sinem Civriz; Ozdemir, Evren; Altuntas, Fevzi (CIG MEDIA GROUP, LP, 2016)In this retrospective, multicenter study, we evaluated the real-life outcomes of adult Philadelphia-positive acute lymphoblastic leukemia patients. The best results in terms of survival are achieved in patients who were ... -
Aldosterone Synthase CYP11B2 Gene Promoter Polymorphism in a Turkish Population With Chronic Kidney Disease
Yilmaz, Meral; Sari, Ismail; Bagci, Binnur; Gumus, Erkan; Ozdemir, Ozturk (IRANIAN SOC NEPHROLGY, 2015)Introduction. It has been shown that gene polymorphisms influence the development and progression of chronic kidney disease (CKD). Many studies have indicated that aldosterone synthase CYP11B2 gene polymorphism (-344C>T) ... -
Antioxidant-oxidant status in patients with hydatid cyst
Bakir, Sevtap; Celiksoz, Ali; Celik, V. Kenan; Sari, Ismail; Aydin, Huseyin (WALTER DE GRUYTER GMBH, 2012)Objectives: To determine whether oxidative stress plays a role in the pathogenesis of hydatid cyst by examining levels of total antioxidant status, total oxidant status, oxidative stress index, and activities of the enzymes ... -
Association between the soluble epoxide hydrolase gene and preeclampsia
Sari, Ismail; Pinarbasi, Hatice; Pinarbasi, Ergun; Yildiz, Caglar (TAYLOR & FRANCIS INC, 2017)Objective: In this study the association between K55R polymorphism, methylation level of the EPHX2 promoter region, and PE was investigated in 520 individuals including 260 PE patients and 260 healthy pregnant women.Methods: ... -
The Clinical Characteristics and Therapeutic Outcomes of Elderly Patients with Chronic Lymphocytic Leukemia: A Retrospective Multicenter Study
Tombak, Anil; Tiftik, Naci; Dogu, Mehmet Hilmi; Sari, Ismail; Akay, Meltem Olga; Karagulle, Mustafa; Kaya, Emin; Korkmaz, Serdal; Sencan, Mehmet; Akyol, Gulsah; Kaynar, Leylagul; Comert, Melda; Saydam, Guray; Dal, Sinan Mehmet; Ayyildiz, Orhan M.; Yildirim, Rahsan; Kiki, Ilhami; Kara, Erdal; Esen, Ramazan; Sungur, Mehmet Ali; Erkurt, Mehmet Ali; Altuntas, Fevzi; Unal, Ali; Ilhan, Osman (AMER SOC HEMATOLOGY, 2014)… -
Comparison of Oxidant/Antioxidant, Detoxification Systems in Various Tissue Homogenates and Mitochondria of Rats with Diabetes Induced by Streptozocin
Celik, Veysel Kenan; Sahin, Zeynep Deniz; Sari, Ismail; Bakir, Sevtap (HINDAWI PUBLISHING CORPORATION, 2012)Objective. Oxidative stress is considered to be the main factor in the development of diabetic complications and tissue injury. our objective was to investigate and compare the oxidant/antioxidant conditions and detoxification ... -
Comparison of sulfur transferases in various tissue and mitochondria of rats with type 1 diabetes mellitus induced by streptozotocin
Aydin, Huseyin; Celik, Veysel Kenan; Sari, Ismail; Tekin, Yusuf Kenan; Demirpence, Ozlem; Bakir, Sevtap (SPRINGER INDIA, 2016)This study aims to investigate the relationship between sulfurtransferase (STS) activities [rhodanese (TST), mercaptopyruvate sulfurtransferase (MST)] involved in the catalysis of several biochemical reactions including ... -
DETERMINATION OF SERUM ADENOSINE DEAMINASE AND XANTHINE OXIDASE LEVELS IN PATIENTS WITH CRIMEAN-CONGO HEMORRHAGIC FEVER
Celik, V. Kenan; Sari, Ismail; Engin, Aynur; Yildiz, Guersel; Aydin, Hueseyin; Bakir, Sevtap (HOSPITAL CLINICAS, UNIV SAO PAULO, 2010)OBJECTIVE: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo ... -
Diffuse Large B-Cell Lymphoma in adults aged 65 years and older: A retrospective multicenter analysis of clinical characteristics and therapeutic outcomes
Dogu, Mehmet Hilmi; Keklik, Muzaffer; Terzi, Hatice; Korkmaz, Serdal; Erkurt, Mehmet Ali; Cagliyan, Gulsum Akgun; Kaynar, Leylagul; Sivgin, Serdar; Sari, Ismail; Keskin, Ali; Sencan, Mehmet; Altuntas, Fevzi; Ilhan, Osman (CIG MEDIA GROUP, LP, 2015)… -
Effect of tumour necrosis factor-alpha and interleukin-6 promoter polymorphisms on course of Crimean-Congo hemorrhagic fever in Turkish patients
Yilmaz, Meral; Elaldi, Nazif; Bagci, Binnur; Sari, Ismail; Gumus, Erkan; Yelkovan, Izzet (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015)Objective: In this case-control study, we investigated whether IL-6 (-174G/C) and TNF-alpha (-308G/A) gene polymorphisms affect the clinical course and outcome of CCHF. Methods: Total 150 patients with CCHF and 170 controls ... -
Effects of vitrification and transplantation on follicular development and expression of EphrinB1 and PDGFA in mouse ovaries
Gumus, Erkan; Kaloglu, Celal; Sari, Ismail; Yilmaz, Meral; Cetin, Ali (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018)The aim of this study was to assess the follicular development and the patterns of EphrinB1 and PDGFA immunostaining in vitrified mouse ovarian tissue (OT) with and without transplantation. Histological evaluation was ... -
Erythrocyte Sedimentation Rate, Serum Amyloid A and C-reactive Protein Levels in Patients with Acute Brucellosis
Celik, V. Kenan; Sari, Ismail; Bakir, Sevtap; Engin, Aynur; Bakir, Deniz; Sari, Musa; Poyraz, Omer; Yildiz, Gursel (PROFESSIONAL MEDICAL PUBLICATIONS, 2011)Objective: To determine the levels of and the relationship between serum amyloid A (SAA), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in patients with acute brucellosis. Methodology: SAA, CRP and ESR ... -
Evaluation of the relationship between serum levels of VEGF and sVEGFR1 with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever
Bakir, Mehmet; Bakir, Sevtap; Sari, Ismail; Celik, Veysel Kenan; Gozel, Mustafa Gokhan; Engin, Aynur (WILEY-BLACKWELL, 2013)The most accepted view to explaining the pathogenesis of Crimean-Congo hemorrhagic fever (CCHF) is endothelial damage. This study was conducted in a University hospital to investigate the serum levels and prognostic ... -
Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer
Oz, Muhammed; Karakus, Savas; Yildirim, Malik; Bagci, Binnur; Sari, Ismail; Bagci, Gokhan; Yildiz, Caglar; Akkar, Ozlem; Cetin, Ali; Yanik, Ali (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2018)Aim: Although several associations were found between Dicer rs3742330 single nucleotide polymorphism (SNP) and development and prognosis of some epithelial cancers, relationship between the SNP rs3742330 and endometrial ... -
Investigation of LAMTOR1 gene and protein expressions in germinal vesicle and metaphase II oocytes and embryos from 1-cell to blastocyst stage in a mouse model
Gumus, Erkan; Sari, Ismail; Yilmaz, Meral; Cetin, Ali (ELSEVIER SCIENCE BV, 2018)Improving the success of in vitro fertilization (IVF) and infertility treatment depend on understanding basic cellular and molecular mechanisms of human preimplantation development. Pre-implantation mouse embryo model is ... -
Lack of Association between the MTHFR C677T Polymorphism and Lung Cancer in a Turkish Population
Yilmaz, Meral; Kacan, Turgut; Sari, Ismail; Kilickap, Saadettin (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)Background: In this case-control study, we aimed to investigate the relationship between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials and Methods: Total 200 individuals ... -
Oxidative stress in the adult and pediatric patients with Crimean-Congo haemorrhagic fever
Aydin, Huseyin; Guven, F. Mutlu Kukul; Yilmaz, Abdulkerim; Engin, Aynur; Sari, Ismail; Bakir, Deniz (MALARIA RESEARCH CENTRE, INDIAN COUNCIL MEDICAL RESEARCH-ICMR, 2013)Background & objectives: Crimean-Congo haemorrhagic fever (CCHF) can be fatal with bleeding, shock and disseminated intravascular coagulopathy (DIC). Although similar genetic strains have been defined, the causes of the ... -
Philadelphia-positive acute lymphoblastic leukemia in daily practice: A multicenter experience.
Goker, Hakan; Tekgunduz, Emre; Sari, Ismail; Pala, Cigdem; Dogu, Mehmet Hilmi; Ozturk, Erman; Turgut, Burhan; Korkmaz, Serdal; Demiriz, Itir Sirinoglu; Buyukasik, Yahya; Hacioglu, Sibel Kabukcu; Kaynar, Leylagul; Bozdag, Sinem Civriz; Altuntas, Fevzi (AMER SOC CLINICAL ONCOLOGY, 2013)… -
Primary central nervous system lymphoma in daily practice and the role of autologous stem cell transplantation in relapsed disease: A retrospective multicenter study
Erkurt, Mehmet Ali; Berber, Ilhami; Tekgunduz, Emre; Dogu, Mehmet Hilmi; Korkmaz, Serdal; Demir, Cengiz; Yilmaz, Mehmet; Akay, Olga Meltem; Pala, Cigdem; Bilen, Yusuf; Kaya, Emin; Sari, Ismail; Sencan, Mehmet; Kuku, Irfan; Altuntas, Fevzi; Dal, Mehmet Sinan; Aydogdu, Ismet (PERGAMON-ELSEVIER SCIENCE LTD, 2016)We investigated the course of 54 patients presenting with primary central nervous system lymphoma, who were treated in daily practice. The patients were treated with chemotherapy and/or radiotherapy and/or intrathecal ... -
Significant association between MDM2 T309G polymorphism and colorectal cancer
Atabey, Mustafa; Tas, Ayca; Sari, Ismail; Bostanci, Meric Emre; Topcu, Omer; Silig, Yavuz (IMPRIMATUR PUBLICATIONS, 2019)Purpose: The Murine double minute 2 (MDM2) gene plays a crucial role in regulating and suppressing the function of apoptotic pathway. We investigated the relationship between MDM2 gene SNP309 (T309G) (rs2279744) polymorphism ...